Leak-free, low-noise circulation pump for cooling and temperature control circuits in bioreactors and fermenters in medical OEM systems

MARCH M1 – compact, magnetically coupled 24V centrifugal pump for reliable temperature control in biotechnological and medical systems

In modern fermentation and bioreactor systems, precise temperature control is essential for process stability, reproducibility, and product quality. Cooling and temperature control circuits must reliably remove process heat or supply heat as needed, without fluctuations that could interfere with biological processes.

For these requirements, the magnetically coupled MARCH M1 is an ideal compact, leak-free, and low-noise circulation pump with a 24V BLDC/EC drive. It is designed for applications where stable flow, high operational reliability, easy OEM integration, and low-maintenance continuous operation are critical.

Application data / process requirements:

Application: cooling and temperature control circuits in bioreactors, fermenters, and medical technology peripherals
Typical media: water/glycol and comparable temperature control fluids
Requirement: stable, continuous flow for precise and reliable temperature control
Operating mode: designed for continuous duty in typical 24/7 applications
Key criteria: low noise, minimized leakage risk, high operational reliability
Integration: compact design, common connection options, reliable start-up behavior

Pump type used / technical specifications:

M1 series, magnetically coupled centrifugal pump with 24V BLDC/EC drive

Drive: 24V EC/BLDC drive, brushless, typ. 7 W, electronically commutated with integrated control electronics
Electrical connection: simple two-wire connection (+/-)
Design: space-saving configuration due to outer rotor motor design
Noise level: whisper-quiet operation with ≤ 40 dB(A)
Max. flow rate: up to 8.4 l/min
Max. head: up to 4 m
Wetted materials: PP, POM (Delrin), PSU
Temperature ranges (depending on material): PP up to 70 °C, POM up to 90 °C, PSU up to 121 °C
Connections (depending on model): 3/8" female thread, 1/4" NPT, 3/8" and 1/2" hose connections

The application

Fermentation and bioreactor systems are used in highly critical biotechnological processes – from early-stage research and process development through to industrial-scale production of active ingredients and vaccines. In these applications, parameters such as temperature, pH value, oxygen supply, and feeding regime directly affect cell growth, yield, and product quality.

Temperature control is one of the most safety-critical elements of the surrounding system infrastructure. Cooling and temperature control circuits ensure that heat is reliably removed or supplied as required. Even minor temperature deviations can compromise process stability and negatively affect sensitive biotechnological workflows.

In vaccine manufacturing, active ingredients are often processed and diluted after cultivation, transferred into sterile single-use containers, and then moved to downstream production and filling systems. This process chain places particularly high demands on the operational reliability and dependability of all peripheral components involved.

Why use a magnetically coupled 24V centrifugal pump?

In sensitive medical and biotechnological applications, leak-free, low-maintenance, and low-noise pump solutions are especially important. The magnetically coupled design of the MARCH M1 eliminates conventional dynamic seals and therefore significantly reduces leakage risk and maintenance requirements.

The compact 24V BLDC/EC drive makes the pump ideally suited for OEM integration into devices, skids, and modular process systems. At the same time, its smooth and quiet operation supports use in laboratory environments, diagnostic systems, clinical settings, and other noise-sensitive applications.

With a flow rate of up to 8.4 l/min and a maximum head of up to 4 m, the M1 offers an ideal performance profile for many cooling and temperature control tasks in biotech, medtech, and device peripheral applications.

Additional medical applications for the M1

Patient temperature management: blood and infusion warmers
Blood bank and cell/gene applications: plasma/FFP thawing, cell material thawing, therapy manufacturing peripherals
Bioprocess peripherals: bioreactor/fermenter temperature control, single-use skids, modular process units
Minimally invasive surgery: irrigation/fluid management and fluid warming
Urology / laser medical technology: water cooling circuits in laser systems

Why the MARCH M1 is the right choice

Leak-free due to magnetic coupling: reduces leakage risk and minimizes maintenance in sensitive environments.
24V BLDC/EC drive: ideal for OEM integration into medical devices and skid-based systems.
Very low noise operation: suitable for noise-sensitive laboratory and clinical environments.
Well-matched performance profile: up to 8.4 l/min and up to 4 m head for cooling and temperature control circuits.
Flexible material options: PP, POM, and PSU for a wide range of temperature and media requirements.
Easy integration: compact design and common connection options simplify engineering and service.

More information:

Pump M1 technical data

Other MARCH pump series suitable for medical technology applications available on request